Pilot Grant

Regenerative Rehabilitation Pilot Grants

Request for Applications

The AR3T Pilot Funding Program supports researchers in the development of innovative, interdisciplinary Regenerative Rehabilitation research projects. AR3T is soliciting pilot grant applications, and will award up to $300,000 in this funding cycle.

Overview: Stem cells interpret mechanical forces in a broad spectrum of ways that can affect their behavior and, ultimately, their ability to drive tissue regeneration. AR3T is looking to support researchers who propose interdisciplinary approaches combining regenerative medicine with mechanical stimulation, with the aim of optimizing outcomes.

sd The Regenerative Rehabilitation research community will benefit from the development of novel lines of research that incorporate methods utilizing mechanical stimulation of stem cells and/or tissue engineering approaches, and assessing stem cell behavior and/or functional outcomes.

The proposed project must include both a regenerative medicine/stem cell biology component as well as a rehabilitative/mechanotransductive component. Contact ar3t@pitt.edu if you would be interested in forming a collaboration with an AR3T researcher on a proposal.

Eligible Individuals: The AR3T pilot funding program is open to junior investigators and mid-level career faculty. The Principal Investigator (PI) should have a doctoral degree in a relevant field and be employed at an nonprofit institution within the United States. The goal is to fund researchers who are interested in beginning a career in Regenerative Rehabilitation research or who would like to start a new line of research in this area.


  • Up to $300,000 will be distributed for the 2018 AR3T funding cycle.
  • Three pilot grants of $50,000/year for two years will be awarded.
  • Total award includes indirect costs by the awardee’s institution.

Key Dates

RFA Release Date: September 1, 2017
Letter of Intent Date: December 1, 2017
Invitation to Round 2 Date: December 21, 2017
Round 2 Application Due Date: February 28, 2018
Notification of Award Date: March 31, 2018
Anticipated Award Start Date: July 1, 2018

If you have any questions, please contact ar3t@pitt.edu.

Examples of funded pilot projects include:

  • Michael Modo (University of Pittsburgh): Neuro-biological effects of rehabilitation on neural stem cell transplantation after stroke
  • Sarah Heilshorn (Stanford): Protein-engineered nerve guidance conduits for peripheral nerve injury recovery and rehabilitation
  • Jarrod Call (UGA) and Sarah Greising (USAISR): Protein-engineered nerve guidance conduits for peripheral nerve injury recovery and rehabilitation
  • Joseph Roche (Wayne State): Novel rehabilitative interventions for muscle loss
  • Ngan Huang (PAVIR): Nano-aligned scaffold conjugated with insulin-like growth factor-1 mRNA for treatment of volumetric muscle loss
  • Riccardo Gottardi (University of Pittsburgh): R-CaRe-Rehabilitation for cartilage regeneration
  • David Mack (University of Washington): Electromechanical maturation of iPSC-derived myotubes in vitro

Additional Information

We are no longer accepting applications for the 2017 Pilot Grant Competition. Subscribe to the AR3T newsletter in order to receive the latest news on research and grant opportunities for Regenerative Rehabilitation researchers.

Review the application process and review criteria for more information.

For questions and/or assistance with proposal development, contact us at ar3t@pitt.edu.