Application Process

Proposal submission will involve two rounds: an initial LOI followed by invitations from AR3T to submit full proposals.

Round 1 Letter of Intent: The applicant is required to submit a Letter of Intent (LOI) that consists of a project name, investigator information (names of PI and collaborators, institutional affiliations, sponsoring organizations, and email addresses), a short description of the project, and a project summary (3 sentence maximum).

The LOI should be submitted by July 1, 2017. Selected proposals will be invited to participate in the Round 2 application process, starting on August 1, 2017.

Round 2 Full Proposal: The full proposal should be uploaded as a PDF file, and should meet the following requirements:

  1. Cover Letter from PI(s) including a statement of the relevance of the proposed work to the field of Regenerative Rehabilitation.
  2. Research Plan: The research proposal will generally follow an R03 format and should include:
    1. A one-page specific aims
    2. Brief background, preliminary studies, methods, timeline (limited to a total of 4 pages)
    3. Address the resources available to support the proposed work
    4. References
  3. Budget & Budget Justification: Please note that
    1. The budget must include both direct and indirect costs
    2. PI salary support must be limited to 15% of direct costs
    3. The budget cannot cover conference travel
    4. Inclusion of capital equipment will be considered on a case-by-case basis
  4. Address Compliance Issues
    1. Animal studies must include a Vertebrate Animals section
      1. Concise description of procedures involving animals, identifying species, strains, ages, sex and total number to be used by species
      2. Justification for the appropriateness of the species for the proposed research; and an explanation for the use of proposed species versus alternative models
      3. Interventions to minimize discomfort, pain, distress and injury
      4. Justification for the euthanasia method if not consistent with the AVMA Guidelines for the Euthanasia of Animals
    2. Assurance of IACUC and/or hSCRO approval and of completion of NIH-mandated responsible conduct or research training, where indicated, must be furnished after Award notice and before funds can be released.
  5. Investigator Biosketches: Biosketches are limited to four pages.

The Round 2 application deadline is October 1, 2017. Award Notifications will be sent out by November 1, 2017, for a January 1, 2018 start date.

Additional Information

Please see review criteria for more information.
Access the online grant application April 1, 2017.
If you have any questions, please contact ar3t@pitt.edu.